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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000362982 HSGN-94 10MM 1ML
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5000376559 5 -O- 4 4 -DIMETHOXY 100MG
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Medchemexpress LLC Disuccinimidyl sulfoxide | 1351828-03-9 | MFCD30497419 | 99.8% | 388.35 g/mol | C14H16N2O9S | 500MG
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Disuccinimidyl sulfoxide (DSSO) is a homobifunctional, amine-reactive, sulfoxide-containing cross-linker developed for cross-linking mass spectrometry workflows. It incorporates two symmetric CID-cleavable sites that produce characteristic fragmentation patterns, enabling confident identification of cross-linked peptides and aiding structural proteomics and protein interaction mapping.
- MS-cleavable sulfoxide core for characteristic CID fragmentation.
- Homobifunctional, N-hydroxysuccinimide ester reactivity toward primary amines.
- Enables confident identification of cross-linked peptides in proteomics studies.
- High purity (≈99.8%) white to off-white solid.
- Suitable for cross-linking model peptides, proteins, and multisubunit complexes.
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eMolecules 3-AMINOQUINOLINE-8-CARBOXYLIC ACID | 1799412-39-7 | MFCD28133462 | 1g
AstaTech | 3-AMINOQUINOLINE-8-CARBOXYLIC ACID | 1g | 410711960 | 33246 | 95.000 | 1799412-39-7 | MFCD28133462 | 188.186 | C10H8N2O2
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eMolecules 3-AMINOISOQUINOLINE-8-CARBOXYLIC ACID HCL | 1337882-40-2 | MFCD28291832 | 1g
AstaTech | 3-AMINOISOQUINOLINE-8-CARBOXYLIC ACID HCL | 1g | 200614905 | 68507 | 95.000 | 1337882-40-2 | MFCD28291832 | 224.640 | C10H9ClN2O2
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Cambridge Isotope Laboratories 1 2 3 4 6 7-HexaCN (PCN-66) (unlabeled) 100 ug/mL in nonane 1 mL
1 2 3 4 6 7-HexaCN (PCN-66) (unlabeled) 100 ug/mL in nonane 1 mL
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5000370785 PRMT5-IN-31 5MG
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5000435085 7-DEAZAXANTHINE 10G
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TARGETMOL CHEMICALS INC 9-Phenanthrol 200MG
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Also available in 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. 9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel. Purity 98.72%
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Apexbio Technology LLC Refametinib 923032-37-5 200mg
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Refametinib (CAS 923032-37-5) is an orally bioavailable selective allosteric inhibitor of mitogen-activated protein kinase kinases MEK1 and MEK2 It binds to an allosteric site distinct from the ATP-binding pocket thereby inhibiting MEK1 and MEK2 enzymatic activity (IC50 19 nM and 47 nM respectively) and blocking phosphorylation of ERK without interfering with ATP binding Refametinib demonstrates potent inhibition in human tumor cell lines with EC50 values ranging from 2 5 to 15 8 nM and suppresses proliferation in BRAF V600E-mutant lines (GI50 67 89 nM) It induces tumor growth delay and regression in xenograft models supporting its utility in cancer research
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Apexbio Technology LLC NSC 74859 501919-59-1 200mg
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NSC 74859 (CAS 501919-59-1) also known as S3I-201 is a selective inhibitor of the signal transducer and activator of transcription 3 (Stat3) pathway S3I-201 disrupts Stat3 DNA-binding activity exhibiting an IC50 of 86 M in vitro with minimal inhibitory effects on Stat1 and Stat5 It also impedes the formation of Stat1-Stat3 and Stat1-Stat1 complexes with IC50 values of 160 M and 300 M respectively In NIH 3T3/v-Src fibroblasts S3I-201 reduces constitutive Stat3 activation and pTyr-705 Stat3 levels induces apoptosis at 30 100 M and downregulates cyclin D1 Bcl-xL and survivin expression This compound is widely utilized in research to interrogate Stat3 function in cellular transformation and oncogenic signaling pathways
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5000371251 MPEG-AMINE MW 750 100MG
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eMolecules 2-FLUORO-5-4 4 5 5-TETRAME 1G
5000211082 2-FLUORO-5-4 4 5 5-TETRAME 1G
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Apexbio Technology LLC SCH772984 TFA 942183-80-4 (free base) 200mg
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SCH772984 TFA is a small-molecule inhibitor targeting extracellular signal-regulated kinase 1/2 (ERK1/2) It is designed to inhibit ERK catalytic activity thereby blocking phosphorylation of downstream substrates and regulating the RAS-RAF-MEK-ERK signaling pathway SCH772984 TFA exerts its biological activity primarily through direct interaction with ERK1/2 acting as an ATP-competitive inhibitor Based on these pharmacological properties SCH772984 TFA holds research potential in studies examining ERK signaling s role in oncogenic pathway activation tumor cell growth survival mechanisms and resistance phenomena in various cancer models
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5000388214 O4I1 200MG
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